产品货号：
Z36774
中文名称：
PARK2/Parkin/PRKN抗体
英文名称：
Anti-PARK2/Parkin/PRKN Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PARK2/Parkin/PRKN Antibody |
| 指标别名 | AR JP;LPRS2;PARK2;PARK2/Parkin;Parkin;Parkinson disease protein 2;PDJ;PRKN |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM |
| 基因名称 | PRKN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Parkin |
| 实际分子量 | 52KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Parkin is a RING domain-containing E3 ubiquitin ligase involved in proteasome-dependent degradation of proteins.It is mapped to 6q26.This gene is important for mitochondrial quality control by lysosome-dependent degradation of damaged mitochondria through autophagy,or mitophagy.Parkin is expressed in neuronal processes and cell bodies of neurons,but not glial cells,in the midbrain,basal ganglia,cerebral cortex,and cerebellum.Parkin assimilated with actin filaments,suggesting that it is a cytoskeletal-associated protein.Parkin is identified as a transcriptional repressor of p53 independent of its ubiquitin ligase function.It also has been found that parkin was associated physically with mitochondrial DNA (mtDNA) in proliferating as well as in differentiated SH-SY5Y neuroblastoma cells. |
| Uniprot ID | O60260 |
| 基因名全称 | E3 ubiquitin-protein ligase parkin |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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